Sultanahmet + Kadikoy + Beyoglu
Get lodging near Taksim Square in Beyoglu and drop off bags
Go directly to Sultanahmet and do activities there until ~6pm
Take the ferry from Eminönü to Kadikoy
Do dinner in Kadikoy
Take the metro (Marmaray) to Beyoglu
Do nightlife in Beyoglu
Walk or taxi back to lodging