Sultanahmet + Kadikoy + Beyoglu

Get lodging near Taksim Square in Beyoglu and drop off bags

Go directly to Sultanahmet and do activities there until ~6pm

Take the ferry from Eminönü to Kadikoy

Do dinner in Kadikoy

Take the metro (Marmaray) to Beyoglu

Do nightlife in Beyoglu

Walk or taxi back to lodging